by Myriel Team | Jun 1, 2026 | Therapeutic Discovery & Development
Bresinsky M, Strasser JM, Vallaster B, Liu P, McCue WM, Fuller J, Hubmann A, Singh G, Nelson KM, Cuellar ME, Wilmot CM, Finzel BC, Ashe KH, Walters MA, Pockes S. Structure-Based Design and Biological Evaluation of Novel Caspase-2 Inhibitors Based on the Peptide...
by Myriel Team | May 31, 2026 | Therapeutic Discovery & Development
Bresinsky M, Strasser JM, Hubmann A, Vallaster B, McCue WM, Fuller J, Singh G, Nelson KM, Cuellar ME, Finzel BC, Ashe KH, Walters MA, Pockes S. Characterization of Caspase-2 Inhibitors Based on Specific Sites of Caspase-2-Mediated Proteolysis. Archiv der Pharmazie....
by Myriel Team | May 30, 2026 | Therapeutic Discovery & Development
Cuellar ME, Yang M, Karavadhi S, Zhang YQ, Zhu H, Sun H, Shen M, Hall MD, Patnaik S, Ashe KH, Walters MA, Pockes S. An Electrophilic Fragment Screening for the Development of Small Molecules Targeting Caspase-2. European Journal of Medicinal Chemistry....
by Myriel Team | May 29, 2026 | Therapeutic Discovery & Development
Fuller JL, Shi K, Pockes S, Finzel BC, Ashe KH, Walters MA. Reengineering of Circularly Permuted Caspase-2 to Enhance Enzyme Stability and Enable Crystallographic Studies. ACS Chemical Biology. 2025;20(4):845-857. PMID: 40117490. DOI:...
